When playing through mission 11 on Human mode my son gets to the second room with a trapped soul in it, just after the ghosty guys blow open the doors. There is a blue vine gate that the black stuff covers up. A bunch of enemies pop out of the ground, he kills them and the music stops, but the door stays covered up, he can't shred the vines.
When I played through on regular and hard mode, the doors uncovered and I think I just continued onward but can't remember if I had to do something to get the door uncovered. It seems like a glitch to me, reseting and powering down the system do not change the outcome.