One thing i like about the anime ,they showed early warning signs of dante becoming more like dmc2 dante with the whole "I am starting to get bored fighting demons" attitude . Its a shame dmc4 ruin that character development.
DMC4 didn't ruin it, he developed from being playful but serious about revenge in DMC1 after vergil's death , to more relaxed and laid back Uncle. As time goes, he matures and wises more, but if a close character dies or he faces something that leads to DMC2 "don't speak just die" personality, that would be an awesome sequel to DMC4.
DMC5 starts from there, kill someone close like nero or trish ( nero is important, i don't suggest it), or dante faces something serious that leads to DMC2 personality. ^that storyline+new concepts and expand the universe of DMC with characters and places from the demon world, and humans that are involved in it + new game mechanics, weapons, styles and playable characters.