Ada's default for me. The crossbow is really fun and unique. Shoot the basic enemy in the face and their head will explode. Shoot them with a Pipe Bomb, then melee them into a group for massive damage. Her automatic handgun is good for setting up her one hit kill melee attack, too.
Pirate Leon is pretty beastly, though I haven't unlocked everything yet..
But yeah, I love the sniper rifle and the assault rifle. Quickshot with the assault rifle followed by a bayonnet to their torso is awesome :D --- My Themesong - http://www.youtube.com/watch?v=FE_o0a2IqsM PSN - ZIGZAGZOM http://i.imgur.com/p0VhX.jpg http://i.imgur.com/CfUdQ.jpg
Carla, Ada's default and both Sherries. Leaning towards Carla, but I tend to use Sherry more with randoms who look like beginners so I can keep an eye on their health with medic. --- [It's gettin' much harder to say no, and even harder to say yes.]