professional could be a little difficult if you're still new to the game, i guess. especially if you have agent hunt on (yesterday, two ah players almost annihilated my newbie partner when playing as those bird bows during the first part of jake's chapter 2). during chapter 3, when both characters are separated, my newbie partner could /not/ survive and died many times. he ended up quitting. it was only on veteran.. he probably didn't have more advanced skills such as firearm lv 3, melee lv 3, recovery lv 2, combat gauge boost lv 2 or defense lv 3.
well to be more fair, it was probably his first time playing through jake's campaign (when i took him to both the elephant hunter and sniper, he was able to pick them up).
just be sure you're prepared. the skills make the game much easier, despite people saying that they "barely see a difference." yeah, right.
With appropriate skills it's not that bad (and if you know how to dodge and counter it's even better), surely not the same bs that was RE5 Pro and the AI is invincible as well so playing with one makes it even easier (you can also tell them to focus on one target if you aim at said target and press O). The AI also loves to counter enemies a lot in Pro lol. No Hope is easily harder simply because no skills are allowed on top of the usual stuff.
With lv3 defense,infinite ammo and weapon power up skill, it's really easy on pro mode but still you need to watch out your health as some monster will just took a chuck of your health block very fast.