Yes, but Capcom would have to do it justice. They can't be lazy like they were with Mercenaries 3D.
I'd like to see: - Lots of stages. Public Assembly, The Mines, The Village, Experimental Facility, Ship Deck, The Prison, RE4 Village, The Castle, The Island and Waterworld. In addition, a variety of new stages from across the series and the maps from 6. - Every single character that has appeared in mercenaries and Raid Mode and all their costumes. More characters and costumes that have not made an appearance are added in. - Optional: The ability to select a Mercenaries style. You can switch between the styles that have appeared in 4, 5, Reunion and 6. All characters are compatible with each mode, so you can play a character all the characters across all modes. I realize this is a tall order (RE4 and RE6 characters would need melees to be compatible with the style in 5 and RE5 characters would need melees for 6), but this would be amazing if they did do this. - Tons of loadouts. The ability to switch these loadouts between characters. - All characters should be viable. In Mercenaries 3D, Claire and Jill are pretty garbage. Avoid this. Give Jill back her AOE knee drop, improve Claire, and give Rebecca back her flame spray. Bump up the other horrible tier characters and bring them up a tad. - Preferably not in mission format. Harder map variants can be included, though. So a normal public assembly stage and a harder version, similar to the EX missions. - Keep it recent. Provide DLC updates so people continue to play.
I'd pay full price for all of this. It'd literally be one of my favorite games ever, I've been wanting them to do a standalone Mercenaries title for forever.