Claire's. You know, the one where she meets Steve and the Ashford with the gay voice. Oh wait, wrong game. Sorry. Chris'. You know, the one where he goes to Rockfort Island to save his sister. Crap, that's right.... Seriously though. Leon's.
White Frosty 0003-3206-9583 Do or Die.... or Flirt 3DS Frosty 0387-8776-3890 Yes, I'm a girl. //Joke
Chris' campaign is the best IMO. It makes no qualms about what its trying to be and it is the most consistent when it comes to gameplay and characters.
Leon's is my second favorite, but it becomes down right silly after chapter 2. I'm not sure why people say it is the closest thing to Resident Evil, when it becomes more over the tops and ridiculous than Jake's campaign at times.
Ada's is next, but hers suffers from some really annoying segments. The linear helicopter and boss fight in chapter 5 make playing her campaign kind of annoying.
Jake's campaign is the worst thing in Resident Evil history IMO. I think I might prefer Survivor.
Chris' was my favorite. best progression, less qte's, surprisingly good ending. Good length as well. only thing i didnt like about it was the car chase which was pretty damn dull.
Second would be Ada's. Liked the sub and aircraft carrier sections were great. Also like the fill in the blank set-up to it. only section i didnt liek was the chopper vs simmons fight.
Third Would be Jakes. By far the best characterizations the series has ever had.. Some of the set pieces were hilariously awesome. Only things i didnt like about it were rhe QTE's at the end and a few of the section were either needlessly annoying(slippery slope!) or half assed(stealth sections). Overall though it was good, but kinda on the short side. Also Sherry's ass is a miracle of the universe.
Lastly would be Leons. I DID enjoy his campaign and it does have the best atmosphere, but it also embodies every annoying and poor mechanic in this game which kinda leaves me wondering why people think his is the best. the wonky zombie hit detections, playing dead zombies, tripping over bodies, majority of the cheap deaths, the worst QTE segments, the most cutscenes, the most free enemy hits(from the camera being taken away), the worst case of lacking in direction towards the bosses damage and the list can go on. That said i did enjoy his whole first chapter and bits of pieces of his fallowing chapters, but his campaign was by far the least consistent.