I rented the game. I had intended to play each campaign once before sending it back to gamefly. Was wondering, are the characters in each campaign different enough to warrant a second playthrough in each campaign? Is the experience basically the same?
Candy: Tastes like chicken, if chicken was a candy.
In a few spots, the characters get separated and have to take different paths (most notably in the Jake/Sherry Campaign, where there is a pretty big difference in gameplay at two points.) I wouldn't really make a big deal of it though. Some of the characters also have unique weapons, like Helena's Hydra shotgun (which lets you do a crazy stunt shot with it), Sherry's Stun rod, and Pier's Anti-Material Rifle.