Really enjoying this game. It's pretty simple, but a lot of fun.
Some things I've noticed:
You *can* level up more than once a game on Normal. I pulled it off with a long haul of a game 700+ turns while playing Priest.
Class skills are pretty decent, but a couple are awful. The Preist's wish, for example, is a waste of a skill. Once you've leveled up a class enough, it's unique skills become available to your other characters. Last Stand is probably the only one worth really considering though, but there are other better skills available.
In terms of Perks and Flaws -- Priest has my favorite perk! Double regen! This can make the game a breeze. If you unlock extra perks on a class, grab double regen! My least favorite perks are Intimidating, Unexpected and Cunning. Intimidating reduces the appearance of your mortal enemy by half. Big deal. Unexpected means enemies can't attack the first five turns. It's useless for the rest of the game, and enemies deal very little damage at that time anyway. Cunning gives you -1 cooldown for your fourth skill -- it's not enough of an impact for me, and my fourth skill is usually one of my least used ones.
For flaws -- Zealous is almost a perk. Special monsters appear sooner which means bonus gold and xp sooner! Confused isn't bad either -- you just have to put up with damage for 5 turns before you can retaliate and scoop up a few potions. Cocky is painful, so avoid it. Cautious will kill you late game.
Enchant is the best skill in the game, hands down. Power it up for frequent free upgrades. Add quick and blue potions to reduce the cool downs even further and your character becomes a monster. Skill Elixir, if used correctly, can provide you quick and frequent level ups which again power up your character quickly. These are easily my two favorite skills. If your character doesn't have them, add them as soon as you level up. If you stack lots of blunt and regen, you can stay at full health leaving potions for Skill Elixir uses and bonus xp! This also means you can forgo upgrades that give you potion bonuses since you won't need them and instead work on skill that give you upgrades and level ups more frequently!
Other useful skills - Big Game Hunter (extra xp & gold from killing a unique), Teleport (butt saver), Counterattack (gives you a round to breathe) and Freeze (Counterattack is better).
In terms of upgrades, so far I tend to go for Blunt, Regeneration, Poison, Strength in that order then any damage boosting or gold/xp/upgrade boosts. Blunt is awesome. It can be very effective in minimalizing the damage you receive especially when you have multiple skulls on screen. Regeneration can then heal you up. The damage over time from poison will damage enemies that normally can't be damaged (due to Meat Shield, for example) and can kill off enemies that you might not have had a second chance to attack. Don't underestimate it!
So why is Blunt better than Regen? If you have Blunt 1, Regen 1. Three skulls attack for 6 damage. Blunt prevents 3 damage. Regen would only heal 1, making blunt almost like a Regen 3 in this case.
When you buy new gear, keep a close eye on your bonuses. It's not unusual for you to LOOSE good upgrades when buying new gear! +2 def at the cost of 2 regen? Pass! It's also possible to gain multiple bonuses on new gear. Compare gear carefully and make your choice. Sometimes just going for the extra damage isn't always the way. When buying though, I usually go for anything that increases my regen and damage output.
My strategies anyway. I can almost always get over 700 turns on Normal with a priest.
and i think teleport if able to get you get it... its worth 1 slot, since i can save you at any point... and if upgraded enough, your never going to die, unless you get that 1 unlucky turn when you get up to the 500-700 turns where the entire board is skulls.... hate that...
Seems I tend to die in really stupid ways. I underestimate the damage I'm going to get nailed with.
Anyone know what the formula is for the armor?
I've had luck so far loading up with Enchant, Collect Potions as XP, Teleport (or anything that will clear skulls from the board) and another spell to boost gold (double gold) or upgrades. Basically, I try to get upgrades as quickly as possible.
Also a big fan of quick, blunt, regen (especially with the double regen merit!) and poison. I really didn't think poison was a big deal until someone recommended it. Works wonders too on the invisible skulls. High armor, but low health. Plus, poison works on monsters even when Meat Shield is in play :) So I tend to load up on quick, blunt, regen and poison. I also try to boost my upgrades depending on my skills. I try to focus on gold/xp/upgrade boosts early on when you don't need the damage or health boosts as much.
Got two levels in a game for the second time so that seems to confirm that you can get more than one trophy per play-through.