Okay, if a female toon is just an unplayable support character, a sidekick, or can't carry a game franchise on their own, they're is no way they can be "queen of gaming" if they're in the shadow of someone else in their own series!!
Peach, Zelda, Cortana, and Jill Valentine are all overshadowed by the male protagonists in their own series. Calling them "queen" of anything is absurd.
Honestly, the only contender to Lara Croft is Samus Aran. They're the only two female protagonists that can carry their own franchise by themselves. I guess "Lightning" could count, but is anyone putting her forward? lol