Wouldn't it depend on what your build is/what type of character you're RPing?
I LOVE pickpocket if for only the extra pockets perk. Even if I try a build I wouldn't normally do, I've got that ES problem where I like to pick up tons of stuff. carry weight +100, without having to invest heavily in stamina + the steed stone.... AND the poisoned perk. LOVE it.
but like I said, if you're going all paladin or warrior, I can see why those might not matter. --- It's worked so far, but we're not out yet.
I haven't played as a warrior much, but when I have, a shield with Block perks is amazing. Pickpocketing isn't really useful until you have the thief guild influences but after that it feels pretty cheap.
I'd say pickpocketing. It isn't talked about a lot here and you don't see it in too many builds. You can do some pretty devastating stuff with it, and it's very useful early game for cash. --- KENNEDY: Heavens to Betsy.