I have a PS3, but i have a very high end PC and I want to buy the game for PC of course. My wife wants to watch me play so I'm going to run the game through my TV and I want to buy a wireless gamepad for my PC so i can sit on the couch and relax while i play.
You can always use x360ce if you have a separate controller for your PC --- Currently Playing: Xenoblade Chronicles, Bleach: Soul Ignition, No More Heroes: Paradise, Deus Ex: Human Revolution (PC) PSN: Hoguru
If you can afford the extra 30$ I highly suggest picking up a 360 controller. Just plug the controller into your USB port and Skyrim automatically recognizes it and switches the control type to it. I think you can still map the buttons to the controller but am not 100% sure as I have not tried it.
This game is definetly optimized for a gamepad and not a mouse/keyboard
You may also want to check out the aforementioned MotionJoy. It allows you to use a PS3 controller emulating the 360 pad. I am unsure as to weather you can do so wireless, and what additional hardware you may need to do so.
The game is already programed to accept the 360 pad inputs. Once it's connected you are golden.