Just started hard mode and got hit once and lost a pretty decent chunk of life. I mean i just got hit by grigoris fire at the start and went from full to less than forty points of health...this is going to be fun.
My lvl 121 so most input is enemies are still easy to an extent, mobs still seem the same and early enemies have a slight buff. When selecting hardmode it will start your game over with all currently collected equipment. I don't know the specifics of what was changed but if anyone else is about to go hard mode tell me what it says when selecting the difficulty.
Don't know much aboit speedrun other than its played offline.
Hope this helped
Edit: stamina consumption seems to be higher because i cant use as many abilities in succession as before. -- GT: Neo Peace Maker Pawn: Tsukiumi