At least in multiplayer we already know it ties in with the novels, seeing how it all takes place on the ship UNSC Infinity with everyone playing as Spartan IV's --- "I'm gonna pay him a...what do you call it? A beating! Yeah, I'm gonna pay him a beating!"
Glasslands itroduced the infinity ship and the spartan 4s but not too much was said about them. Hopefully the next noval willl provide more info other than the spartan 4s are soldiers who volunteered for the program. There is also suppossed to be a third book but what getts me is the thursday war is coming out in october and we really dont know when the game is coming out so if the third book has anything to dowith halo 4 it would have to be between 4 and 5 or something. --- GT: Kaiju Spartan. "No you're doing it all wrong here let me show you" "Nice demonstration sarge""oh shut up". (Red vs. Blue).
I didn't care for much of the book (not enough research into the lore and as such, poor characterization), but I'm glad that 343i is doing what Bungie never did much of, and that's bringing the greater story in line with the games.