Red Dead Revolution (or whatever R word they decide to use) or Bully 2 if they decide to make that - but please for the love of god take away that annoying sleeping feature that restricted you from really exploring the world. I would definitely prefer the next Red Dead though.
After that, I would like something similar to LA Noire if it's possible. I actually really liked that game. Imagine the next Red Dead and LA Noire on next gen consoles.. *drools*