Do sidequests ever cancel out???

#1MrMojoRisin357Posted 9/21/2012 6:06:30 PM
Due to an advance in the main story plot?
#2bman0123Posted 9/21/2012 6:09:42 PM
I did a side quest where it required me to talk to that guy missing an arm in the wayy beginning.
He wasn't in the first place anymore so I had to turn in the quest in his current location which was sanctuary.
#3caramel_codPosted 9/21/2012 6:15:01 PM
To my knowledge, not unless the quest-giver dies. As you might imagine, this doesn't happen often.