I've been having a heck of a lot of fun running a Melee Zero Class. Very self-sufficient but also a bit of a challenge running with the Love Thumper. Long recharge rate but extra Melee Roid damage leaves you exposed for major damage... Hm, I kind of want to do a complete melee run through campaign now..
Xbox 360 Gamertag: DoS Paper Clock Will Farm For Food.. </3
Zero and Sal would be better (imo). They both provide different playstyles. Zero is more about tactics and precision, with lower health options in return for a higher damage output. Sal is about spraying bullets in every direction whilst running around in circles very fast.
Both good in their own way. It's really up to you.