I just got back into the game and decided to work on my Siren. I switch between a Cataclysm/Motion (solo) and Harmony/Motion (multiplayer) build, and I've got great class mods and relics for my sets. What I really need help with is narrowing down some good weapons, grenades, and shields for her. Please help.
Weapons: appropriate Elemental paired with Witch or Fox class mods. SMG's paired with Cat class mod. Grenades: Breath of Terramorphous paired with Fox class mod and a +fire damage relic is devastating Shield: Evolution. health boost+health regen+ elemental protection
You can take my Karma, but you'll never take......MY FREEDOM!
I like to just load up on lots of different elements but mainly I run with a Volcano, Hellfire and Teeth of Terra/Blockhead so everything dies in horrible, firey pain. I don't really care for SMGs but the Hellfire is good fun. I've got a ton of other things but they're all subjective. Mostly just stick mix up the elements, especially in TVHM where they mix up what you fight a lot.
Greenade wise I carry a fire leech and a storm front.