Grimrock doesn't have turn-based combat like EO, and as far as I can tell, no town/hub to do things like shopping or healing. It's straight up "This is where you are, this is what you start with (character creation aside), now try to get out." I would imagine there's a rest system or something for healing, I do know there's a food/hunger system of some sort.
It DOES have that exploration element of EO. I foresee a lot of time spent trying to figure out how to open things or get past puzzles, or looking for every little secret wall to get that extra bit of goodies.
What I'm wondering is if monsters respawn eventually. I don't exactly want to grind, but if I get lost and can't figure out how to open something or get through a room I at least want to get distracted by more monsters.
The game is all about making you feel alone and hopeless. Some of the rooms shown in the trailer honestly looked more annoying than anything (rows of trapdoor floors opening and closing at a fairly quick pace, etc.), but hopefully they won't be as hard to pass through as they seemed to me.
I'd give it a shot at least. It's $12 if you preorder from www.grimrock.net right now. For $12 even if I hate it at least I'm not out $30+ like I would be with a DS or console game.