I can't stand it. Just like I always thought about Monster Hunter, the lock on ability adds absolutely nothing and makes it harder to maneuver your character where you want them to be. Locking on to an enemy encourages you to just run right up to it instead of making it easier to move around it however you like.
Sometimes I accidentally lock on to enemies and it drives me bat**** until I can get it to turn off again, it's that bad.
Official Censored Element of the Fraternal Order of Monster Hunter Gentlemen.