will i lose anything by choosing the lowest difficulty?

#1kst8erPosted 7/24/2012 2:31:19 PM
are there certain parts of the game that will be made unavailable or locked off if i lower it down to the easiest setting? i know certain achievements will be unattainable. but other than that is there anything that anyone can think of?
"I consider myself an artist, but I would give it all up for a boatload of money" Jim Gaffigan