She Hulk is the best bruiser right out of the box. She doesn't need a whole of buffs lot to do okay damage and has a stun attack, and can go twice every other turn.
Iron Fist recently got a buff, but he's always been a great unarmed scrapper. great for taking out inflitrators, his Iron Fist move does wicked damage, and he can help set up other teammates for combos.
Ms Marvel is a great blaster. She can go twice every other round too. Her last power isn't that great, but she does excellent damage.
Invisible Woman is one of my go-to Infiltrators still. She can shield the team all day long, her telekinetic spheres do decent damage and she's the only character in the game that can completely lock out an enemy.
And of course, Scotty recently got a buff and he's a great character now. Counter attacks and followups all day long.
I tell everyone if they plan on starting a new game. Get the 15-pointers first. They're cheap, they're all great in their own way, it'll boost your roster and have classes for every mission.
"His words are but a sauce to digest his wit." Tangerine, Tangerine. Living reflection of a dream....