Works very well on Windows 7 through Steam, I just had to use the "Set Launch Options" tab to make a few performance adjustments like custom resolution, skipping intro and forcing 1 core only (the game is not optimized for multi-core CPUs). In game, I set graphics to software mode, and turn shadows off. After that the game is running very smoothly.
Works fine on Win 7 for me, only tweak that I needed was the high rez tweak. Game hasn't crashed yet.
Simtropolis has pretty much every mod you could ever want.
Heads up: There are lots of mods out there that multiply the number of jobs created by all industries and commercial services, but some of them already include a fix for some places missing jobs. If you're going to use a multiplier mod, you probably wont need the fix seperately.
http://whc.unesco.org/en/list/666 Lumbini, the Birthplace of the Lord Buddha. Mind=blown.