I play without it on all of my class. Toughness is the least useful perk in my opinion. I barely get into gunfights where both me and the enemy are shooting each other at the same time. Usually he dies first, or I do. But considering this game's lag, I usually die.
yea it's really not that useful, doesn't make that much of a difference. And like the other guy said, i'm rarely in those situation where we're both shooting at each other. I have it on my target finder lmg class, and i'm trying to get the challenges for toughness done. So might as well keep it on there till i finish.
of course EVERYTHING looks bad if you remember it. -homer simpson