Okay, my friend and I are apparently faced with a never ending swarm of enemies (Necromorph and Shadow-Pack). We're in the last room of this mission, we can see the storage box, but we can't reach it.
During the last Insanity moment, I hit the Marker and that seemed to get me out of it, now we can't figure out why they just keep spawning! They won't die! We have an entire stock of ammo, but we inevitably run out because nothing we do seems to end the sequence.
Find me on deviantArt - FerusDemens or on Xbox Live - Ferus Demens
Like the above said, you have to hit it a bunch. I think it's based on hits and not damage done, so I hope you brought a machine gun (that solved the thing in like 5 seconds for me on my impossible run).