I'm sorry, but the best soundtrack in a game belongs to Donkey Kong Country 2: Diddy's Kong-quest.
SonicSonic 2Sonic 3 & KnucklesStreets of RageStreets of Rage 2Streets of Rage 3Castlevania SotNJet Grind RadioJet Set Radio FutureHalo 2 has a great soundtrack, but there's no way it's the greatest. I haven't even played much Nintendo or Playstation, but I bet there's a bunch of great soundtracks from their end as well.
jet set radio/jet set radio future <<<<<<<<<<<every game to ever exist
You are not allowed to request a sticky.