Unfortunately I just haven't had the time to watch The Walking Dead TV series yet. I've heard amazing things about the game though and I was just wondering if knowledge about the TV show is vital to understanding the game?
Nope, it's a standalone story that takes place along the same timeline as the beginning of the show but there's also some cameos from characters from the comic and the show. There's also a spoiler somewhere in the game, a pretty important bit of information that isn't revealed in the show until the 2nd season. That's about it as far as the game's connection to the rest of the Walking Dead universe goes.