I'm assuming this dosen't count temporary boxing to use an HM slave to get through an area? Then no. I always use my starter at least until after the E4 and even then I still tend to keep them around. (Especially since my first game of every gen I pick water and I like to have surf onhand.)
Technically no. I just really like the starters very much most of the times and can always get one that I usually really like. Starters are just designed to be that, starters, and they damn fine jobs in doing that. I'm very excited for Froakie this time around and so I can have a surfer (though he probably is going to be more physical inclined isn't he -__-).
As for the technical part. I was playing through Fire red and I just couldn't beat the Elite 4 when I started with Charmander (I still didn't quite get the more specifics and was just having fun) so i ended up transferring everything to my brothers game and restarted and got them back, this time starting with Squirtle
[::[_]::]Common sense [+[_]::]just because you can doesn't mean you should