And with a different route to boot. So like the first gym would actually be Viridian, and instead of going to Pewter you'd take Diglett's Cave to Vermilion. Pewter would be last. Old Man Brock ahoy.
But yeah with changed up routes and new pokemon availability and expanded cities and generally seeing what the world is like as it keeps going. Professor Oak would be Daisy Oak instead of Samuel. Cinnabar would be rebuilt. Lavender would be just FULL of ghosts, having taken revenge on the town for destroying their home and replacing it with a radio tower. Human sacrifice, Growlithes and Meowths living together, mass hysteria.
(I mean it won't happen thanks to the games needing to be tied with the show. Stupid lousy multi-form franchise empire.)
King of the Zelda Wii U WT Board http://i.imgur.com/RK6EB.png