Why did you put Tales of... in your list? I can't think of any Tales of game with a female main.
They all have female playable characters, I mained Presea in symphonia. Then in symphonia 2 Marta and Emil are equally important. In Xillia you can choose to play as Milla or Jude. Or at least who to start off as since you can switch to Milla basically as soon as you meet her. I haven't beaten it but I think Milla is the more important of the two. Unless Jude ends up with a case of The Chosen One Milla is definitely the main character, even if you aren't playing as her. --- Every time I try to go where I really wanna be it's already where I am, 'cuz I'm already there XBL, PSN, Steam, Origin, BSN, GFAQs, MC: PhilOnDez
Aquaria The "Blackwell" series (Legacy, Convergence, Unbound) Sonic Adventure 1 (if you count Amy Rose) L4D1 & 2 Borderlands 1 & 2 Y's Origin Quake III Arena (several female characters) The Wonderful End of the World (a katamari damacy clone with a female protagonist, though you never really see her). --- http://raptr.com/badge/arleas/uc.png http://i.imgur.com/G7PNnZ8.gif
The Legend of Heroes: Trails in the Sky (PSP) Ys Origin (3 story modes, one of them has a female protagonist) (PC) Atelier Totori (most of the Atelier series) --- Trails in the Sky(PSP) has some of the best writing and most fleshed out setting I've seen in a RPG. Check it out if you're looking for an excellent RPG.