I've never had a problem. I checked them once, and load up from a desktop .exe shortcut, and have all my mods working fine. I think it has something to do with people tinkering with their rigs to squeeze every last bit of performance out of them, 'cause mine's a POS...
Oh, meltdown. It's one of these annoying buzzwords. We prefer to call it an unrequested fission surplus. -Mr. Burns
Not only that, the launcher can't even list the damn mods in a vertical order if you have more than 10 or so. At least, it doesn't on my PC, it bunches them up into an incoherent mess. Actually I should say it did, because now it's decided it doesn't want to list .esp files at all, leaving a blank window. FOMM is really the only way to go.
The Hecker Effect Because games are just too complicated for us gamers.