This is so easily Xenoblade Crhonicles. There is no other correct answer.
Honestly, the only people who don't say Xenoblade either don't own a Wii OR play extremely obscure imported games from Japan.
I have a Wii and Lost Odyssey and Last Remnant aren't really that obscure. Xenoblade is a good game, but people should stop saying "the only correct answer is Xenoblade", the game is already enough overrated.
I go to gamefaqs board by jumping on to the internet and then use stuff like "report" and kill the crap outta trolls.
Seriously. When the game's characters aren't being silly, they actually allude to some interesting stuff about gaming, like talking about a one-console future (the games dark ending) and how gaming brings people together (the LAN party scene). Plus some of the attacks look amazing (Force Formation and Apocalypse Nova, in particular, looks awesome)
Not changing this until Capcom either gets their act together or the company goes under (Dragon's Dogma was a good start.)