Breath of Fire reboot with action-combat system (like the Tales series), Ryu slowly fills a gauge up as he attacks, when the gauge is full, overlimit dragon mode can be activated, powering him up to the dragon-hybrid form found in BoF 3 (Warrior/Myrmidon) 4 (default) and 5 (default) whereupon he kicks unholy amounts of buttocks.
The only good Dragon system was the Gene system in 3. An overhaul of Breath of Fire needs that system polished up.
Wishful: Street Fighter 5 done with sprites instead of the hideously ugly SF4 3-D style (like seriously, Capcom, were you TRYING to make the game as visually unappealing as possible?), set after SF3 in the timeline (not a prequel), with all new characters except for Ryu and Ken (like every other numbered SF title before 4 came along), and a good battle system that rewards skilled play instead of the "have a free Ultra for getting your ass beaten" casual-friendly crap that 4 had.
Realistic: Resident Evil 7 (and please try to make it as good as RE2/4, 5 was "meh" and 6 is just a trainwreck in every way imaginable).