None because I don't spend mindless hours trying to grow my e-peen.
Why do posts like this have to exist in every topic about trophies? What makes you think you have the right to determine how others extract fun from the games they play?
Anyway, my roughest plat would have to be Deus Ex: HR because the Cloak and Dagger quest glitched on me costing me not only the trophies associated with the quest itself but also, because of the effects of the glitch, the Pacifist trophy as well, forcing me to do a second playthrough.
I have walked across the surface of the sun. I have witnessed events so tiny and so fast they can hardly be said to have occurred at all...