Nothing that leads to a quest (so walking in on the antagonizer and mechanist fighting doesn't count). For me:
An Abraham Lincoln shrine in the basement of a house. A crazy guy with a whole alley way rigged with mines and mini nukes. Vault 108 *shivers* A three way battle between a mirelurk, a giant radscorpion, and a yiao guai. Brahmin tipping (did it by accident lol)
i fast travelles to caseys garage (vault 112) and was caught in the middle of a three way fight between 2 brotherhood of steel outcasts, several molerats and half a dozen raaiders at least 75 yards away
Haha, I didn't run like a ***** the first time I saw the Behemoth at GNR and it one-shotted Dogmeat and then me right after. Then the second time I ran away screaming.
Small, random? Well, this isn't necessarily random but it suprised me when I first saw it.
When you go to Oasis and talk to The One or whatever those hippies call him. You go talk to him and it turns out to be Harold from Fallout 2 who's been completely taken over by Herbert/Bob (the tree that was sprouting out of his head in Fallout 2). Then he begs you to kill him, rofl.
'God' is an image created out of man's insecurities. - Wiegraf Folles