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I started playing the 360 version and I didn't finish some quests on Feros (fixing the water, food, etc) and was pissed when I found out you couldn't finish the quests once the main boss on that planet was beaten (no, I didn't kill the people either). I will be playing through this on my PC soon and now I know to finish all of those before the boss but I was wondering where else this issue crops up later on in the game?
I was able to finish the Feros quests you mentioned even after defeating the boss (aside from the water one since I accidentally killed that NPC).
I actually can't think of any other quests that you can miss, although there is a point near the end of the story where you won't be able to return to the Citadel to do any of its side-quests. You'll know when it happens though, so it's not a big problem.
Unless you have a very complete list of every quest, it is extremely easy to miss one or two even if you look hard for each quest. To do every quest you must be very determined and mark off each quest from that complete list. Most people dont bother with that and carry a half completed Mass Effect 1 playthrough into ME 2
Plus some of those quests are just dumb invisible until you actually decide to walk along that road. Like, the one with the Doctor on the Citadel. If you didn't go to her after that little shootout (when you're looking for a certain someone), you wouldn't even know there's more to it.
I just changed my personal arsenal to fifteen Metal Gear Ray...... And I'm looking for a target. Who wants to be one? You?
I wish it'd remove the quest out of your journal then. Maybe I'm just too much of a completionist, but I hate having incomplete quests stay there only because I didn't finish them within the small window.
Go to every system, land on all the planets and check out all the POIs on your map. Talk to Garrus and Wrex occasionally to get their conversations/quests. Spam your journal on Feros and Noveria as you'll constantly pick up side-quests there. Explore the whole map! Not planets, but bunkers and the story areas. None of the maps are huge, and they're all very linear. You shouldn't miss anything if you cover all the ground on the maps.
Now the Citadel is just a pain in the ass. Lots of ground to cover, and a billion conversation NPCs for potential quests. I always miss a quest there because I'm being lazy/absent minded/annoyed. Nothing on there is really missable until you can't access the Citadel at the end of the game.
I logged about 32 hours on my first run through the game and missed 2 quests, IIRC? And really Mass Effect is a relatively easy completionist game compared to most.
[EVe *also responds to Santana* Currently Playing: EVE Online, Call of Duty 4, Torchlight
Is there a way to know without having to check everything in a guide? I can understand if you are about to make a huge choice in the game or something and the outcome is obvious that you won't be going back, but to have missions that you can't complete even though the characters are still alive is kind of weird.