I think Ramirez Fiora and Yggdrasil Kayle would be a little odd given the gender swap in both cases.
While not a video game reference, I'd love to see King Corki. I had a late-night epiphany last night when thinking about Bittersweet Lulu that the yordles in general share similar physical traits with the characters in Sugar Rush (Wreck-it Ralph). Corki is especially fitting due to being in a vehicle.
As far as game references, I can see some being interesting. Askanivia (Tales of Symphonia) comes immediately to mind. I'm trying to think of games I've played recently and it's basically Pokemon and League, lol. --- "Why don't you just take this picture for what it is? Teemo being stuffed and mounted by renek." - Serenderpity LoL Name: Thanamar
Trundle as Marth would be oh so sweet http://images2.wikia.nocookie.net/__cb20120411003602/fireemblem/images/b/b3/Marthdlc_img.jpg http://images2.wikia.nocookie.net/__cb20101122194136/leagueoflegends/images/d/d8/Trundle.jpg