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I just read a series of the most terribad brainless recommendations ever.
The real answer is that unless the expected enemy lane AND the enemy jungler are all physical damage, then the MR runes will be better.
The AP blues are a theoretical option, although you may want to consider CDR runes instead depending on what support you're talking about and how you tend to build them.
- Supports with shields/heals may favor the AP - Supports with CC spam may favor the CDR - Supports where you overdose on CDR through items / kit may avoid the CDR - Supports against any opponent lineup with decent magic damage output should stick with MR