Ok so I don't play Annie at all, and I play APC's very little in general, I mostly play jungle, top and support.
I've been thinking of running a Nashor's Tooth along with a Wit's End on her.
The reason I even thought about doing this is because of her AA range. Now I know that it has been suggested in the past that Annie be utilized as an ADC because of her AA range, that's not not what I'm gunning for. Mostly staying AP with some flavoring of on hit-built into her. Even thought about running a Lizard Elder along with the suggested items, but I figured that'd probably be a bit too much.
So the overall build that I am thinking for her (keep in mind I don't play ap):
I know that build is pretty squishy, but I figured it could work since she has the E and her range.. The main thing is I'm trying to see if Nashor's and Wit's can be incorporated consistently into her build with success.
Hope is the first step on the long road to disappointment