I don't think The Grinder universe can overlap with The Conduit universe. Generally speaking, vampires, werewolves, and monsters don't fit in the sci-fi genre very well. I'm not sure why, it just hasn't been done successfully that often, and I think trying to mesh all that continuity would be difficult.
But it's an interesting idea though.
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Well, The Trust does have a history with hybrids and mutants. They could possibly create creatures that are meant to look like Vampires, Werewolves, etc. And according to what I heard on Wikipedia, the characters are hired by a mysterious organization called "Book", similarly to how Mr.Ford is hired by a mysterious organization called "The Trust".
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