Except for Li, who's actually one of my favorite video game bosses.
Lol, Cynthia (Pokémon Platinum) is one of mine. The first challenging boss I've ever encountered. Li was pretty good too. While I was still new at the game, I was having trouble with Li on Low. Brennan beat him on Severe mode perkless with only Rads and USP. Clever strategy.
"I liek pi, 3.141592653589793238462643383279502884197 espasially appul pi."- Khmer