FAQ/Walkthrough by MisterMarioMan

Version 2.00, Last Updated 2009-12-20

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Intro

Hello! This is MisterMarioMan aka John Dunn writing a guide for the critically acclaimed Wii Game, Trauma Center:Second Opinion. This game is filled with difficult operations, new diseases, and, of course, Great Doctors. After purchasing this game, it quickly rose to become one of my favorites, which is why I chose to write a guide for this game and submitted it to GameFAQs. You don't wanna know about me, though, you wanna know about the game. Well, The Guide Follows. Good Luck!

Version 0.10

January 4th, 2008

-Guide Started

-The Following Sections Were Written:

  • Version History
  • Difficulty Levels
  • Rankings
  • Chapter 1
Version 0.30

January 5th, 2008

-The Following Sections Were Written:

  • Chapter 2
  • Chapter 3
  • Contact Me
  • Perfect File
  • Intro
  • Dealing With GUILT
Version 0.40

January 8th, 2008

-The Following Sections Were Written:

  • Mission Types
Version 0.50

January 12th, 2008

-The Following Sections Were Written:

  • Chapter 4
  • Chapter 5
Version 0.60

January 13th, 2008

-The Following Sections Were Written:

  • Chapter Z
Version 0.70

January 14th, 2008

-The Following Sections Were Written:

  • Chapter 6
Version 0.80

January 17th, 2008

-The Following Sections Were Written:

  • FAQ
Version 0.90

January 19th, 2008

-The Following Sections Were Written:

  • Using the Tools
Version 1.00

January 20th, 2008

-Guide Completed

-Layout Compiled

-Guide Submitted

-The Following Sections Were Written:

  • X Missions
  • Outro
Version 1.01

January 23rd, 2008

-The Following Sections Were Written:

  • Legal Stuff
  • Thanks
Version 1.02

April 10th, 2008

-A Few Small Formatting Corrections were made.

-Corrected the S Rank score for mission 6-3.

--The Following Section Were Updated:

  • Contact Me
  • Thanks
  • FAQ
Version 1.50

November 30th, 2008

-Table of Contents recieved a Layout Reformat

-Huge Layout Update Made to All Operations. Several bad spelling/grammar issues were also corrected.

-In the future, the whole guide will be updated with a new improved layout similiar to the one bestowed upon the operations. I also plan on adding to new sections for User Submitted Strategies(Lets see 'em, folks!) And for XSing Tips. Check it soon!

Version 2.00

December 20th, 2009

-Full Update made with the new guide formatting change.

-The Following Sections Were Written:

  • S/XS Ranks

-The Following Sections Were Updated:

  • FAQ

To use the Antibiotic Gel, simply push A. The gel will squeeze out, and then you can move it around to aim where it goes. The vitals will go up as little bit as you use it. Now, the Gel has several uses. It can disinfect the area before you cut into a patient and it can also disinfect the area before you place the bandage. It can be use to fix small holes and cuts in your patient as well, making it a very useful tool. Best of all, this is probably the fastest one to use.

For the Forceps, all you do is press and hold A+B on something. You can then lift it out of the area and move it somewhere else. Remember to be careful with this, for when you set it down, if its not in the right area, you'll recieve a miss. Sadly, that seems to happen A LOT. Oh well, as long as your careful, you should be okay.

The Laser is simple. All you do is press a and the laser will come down. You can use the laser to burn off small tumors and kill several types of GUILT. The only thing you have to watch is where you aim the laser, because if it's centered in one place for too long, it will pop a small hole in the organ. Use the antibiotic gel immediatly or else some blood could collect that you're gonna have to drain. Besides that, the laser is a very simple tool.

The Scapel can be used to cut open a Patient and many other things, making it a very useful tool. However, the sad part is that the scapel is also responsible for the most mistakes. The way the scapel works is that you press and hold A to start cutting, then pretty much just move it around. Theres always a guideline to follow, and you need to follow it CAREFULLY. One wrong move when cutting and BAM! Mistake. In some cases like that, the Patient may even have a new scar to tell his kids about. As long you're slow and careful when cutting, it should be okay, however.

Ugh. If you don't make a mistake with the Scapel, you will with the syringe. After switching to the syringe, you'll see some vials. Theres one green one in every mission, which can be used by pressing and holding A to fill up the Syringe. Then press and hold A on the organ to inject a vital raising juice, which is extremely useful. The other vials will be used the same way although they will be injected into different places for different purposes(Be careful with your aim on these vials!)

The Ultrasound is unique as it really has two purposes, depending on the Mission. It can be the Ultrasound, which is the most common, and is used by pressing A as you move around the Organ. It can detect things such as tumors and kyriaki that hide in the organ. Once detected, the object will remain visible for a short time. The other function of the Ultrasound, found in a couple of missions, is the Magnifier. You push the A button to zoom in on an area on the Organ, and when zoomed in, you push the A button to zoom out. In most of these missions, you must zoom in/zoom out quite often, so make sure you're ready.

The Drain is pretty easy to use. You put in the area that needs draining, and press A to drain. The drains most common use is to drain blood, however it can be used for other purposes, such as draining cytoplasm from a tumor. The drain can be useful, but it's not really used that much.

The Suturing Needle can be used to stitch any wound up. Lets say theres a wound. Pull out the needle, start at bottom of the wound, then zig zag across the wound quickly to stitch it up. At the beginning you'll probably be very bad at it, but later in the game, you'll be able to do it very quickly and accurately. Because of the large amount of wounds in the game, suturing may be the most used trick, so be sure to practice it.

The Bandage becomes available after stitching up an initial cut. You disinfect the area, then you can grab the bandage by clicking the icon to the left. After that, go to the middle of the bottom of the cut, then press and hold A. Strech it across the entire length of the Cut and nothing more, and then let go. It's all bandaged up!

Healing Touch

This is only usable after Mission 2-3(For Derek), or Mission Z-2(For Weaver)

The Healing Touch seems Complicated to most people, but it's actually pretty simple. First, Hold the Z Button, then, hold the B button. After that, Move the cursor to form a star(The Game will teach you how) and your Healing Touch will be a success. Now, after activating the Healing Touch, a bar will appear on the top of the screen. When the bar runs out, the Healing Touch is over, and you can't use it again that operation. Now, the Healing Touch is different for each Character. When playing as Derek, the Healing Touch will slow down Time a bit, allowing you to move faster with fewer interruptions. However. when you play as Weaver, the Healing Touch will cause the vitals to spike way up whenever you pull off a Cool or a Good on a task. As you can see from these tremendous effects, the Healing Touch is a great and powerful tool.

Defbrilator

This is only usable in certain missions.

This will be forced upon you in certain missions. When it is, you'll see a bar. A Green line will move about the bar. You want to press Z+B together right when that line hits in the highlighted section. If it hits near the highlighted Section, you'll have to do it again, but if it hits there again after that, then the patient will be revived. If it is stopped in the highlighted Section, then the patient is automatically revived. Any other section will force you to do it again. You'll have a limited time to do it, so go quick!

Penlight

This is only used in Mission Z-3

Theres one Mission with the Penlight, and it's completely in the Dark. You'll see the Penlight as an Icon to the left of the screen. Click it, and then as you move around the screen a light will surrond your pointer. Once you click an area, the light will stay there until you push the icon again, so you can use that to see the area. It burns out eventually though, forcing you to use the Camera.

Camera

This is only used in Mission Z-3

In the Mission with the Camera, the Screen is completely dark(Similiar to the Penlight.) The Camera, after clicking the icon to the side, will charge up. When it goes off, you'll be able to see the entire screen for a short time. Unfortunetly, it will run out fast, so you should probably memorize as much as you can before it does. Besides providing the area with light for a short time, the Camera has no other function.

Difficulty Levels

This Game Has 4 Levels of Varying Difficulty, Although only 3 are available at start. You are allowed to choose the level of Difficulty as soon as you start the game. The Difficulty Level May Be Changed as the game is played, and for a perfect file, every operation must be complete on every difficulty(For a Total 134 Operations). The difficulty levels are as follows:

  • Easy - Recommended for New Players. The Game isn't too difficult, but there still is a difficult mission or 2 in the bunch to keep it interesting.
  • Normal - If you've played the DS Version or completed Several Operations on Easy, Then You're Ready for Normal mode. It's got a few somewhat difficult operations, but it's not impossible.
  • Hard - I Recommend you've beaten the game at least once and have intimate knowledge of Trauma Centers Gameplay Style. This mode is very difficult, with few missions being easy.
  • Extreme - Incredibly Difficult. Harder than actual surgery.The Extreme Mode is only available for the X Missions. The X Missions are also locked to this mode.

Rankings

Every Operation in this game is based off a simple rating system. Completing an Operation with a Certain amount of Points will get you a certain grade. The Grading System is as Follows:

  • XS Medical Prodigy
    • Can only be aquired on the Hard or Extreme Difficulties.
  • S Master Surgeon
  • A Senior Surgeon
  • B Specialist
  • C Rookie Doctor

Naturally, More Points Will get you better Ranks. However, there are certain things, such as suturing a wound, that will give you different amounts of points. You recieve a message listing how good you did. the messages are as follows:

  • Cool - You've Completed a Task Perfectly. Many Points Awarded.
  • Good - You've Completed a Task, but not that Great. Some Points Awarded.
  • Bad - You've Completed a Task, but completed it poorly. Few Points Awarded.
  • OK - Several Things You can not improve on. OK is a message telling you that you've done as good as you can.
  • Miss - You've made a mistake in performing something. You must retry doing that thing, and no Points Awarded.

Only Some Tasks Give Awards, While Most Give OKs. The following are the listed Tasks that give awards, as well as tips for scoring cools on them.

Let Me Give You an Example. Lets say theres a mission where you must suture 3 wounds. Lets say suturing a wound awards 50 points for a Bad, 100 points for a Good, and 200 points for a Cool. Therefore, the minimum amount of points you can score is 150, while the maxium amount is 600. We'll say the scoring system works like this:

  • XS - At Least 600 Points
  • S - At Least 500 Points
  • A - At Least 450 Points
  • B - At Least 400 Points
  • C - At Least 0 Points

Therefore, to score an XS, you must get a Cool on all 3 suturings. HOWEVER: If you were to score 600 points, but you were on Easy or Normal Mode instead of Hard, You would only score an S. Scoring Cools isn't the only thing to get you an XS, though. To Score an S or XS, you usually have to get every Bonus for the points they award. There are 3-4 Special Bonuses for every Mission, although theres more on that in the Walkthrough. Most of the special bonuses involve going fast and not making a single mistake. Please Note, These Ranks are only for completionists that want to make a perfect game(More on that in the Perfect File Section.) If you just want to beat the game, it doesn't matter if you score a C on every mission.

Mission Types

There Are 2 Types of Missions in this Game, Which I have listed Here.

  • Operation:These are the meat of the game. These missions require that you operate on someone before you can go ahead with the storyline. These can be identified by the diagonal line next to the name.
  • Storyline:These missions don't actually require you do to any work. All these missions do is advance the plot a little more. Generally, there aren't more than 2 missions like this in a row.

GUILT

There are 7 types of GUILT, a strange new disease, found in this game. Below I've listed each type of GUILT, the best way to deal with it, and the Operations it appears in. I definitely reccomend that you read the Triti Section, but besides for that, most of these GUILT are explained in detail the first mission you deal with that specific strain. These full descriptions are really only if you're having problems and need more information.

These are by far the easiest GUILT to deal with. First, for every Kyriaki Operation, you must suture the wounds on the body beforehand. This usually entails of several small wounds and a few large wounds. After taking care of that, 1-3 Kyriaki will appear. These buggers cut the patient up when they appear and when they're cut out. They can also make more cuts as time goes by. I suggest waiting to suture these cuts until all the Kyriaki have been defeated. To defeat a Kyriaki, you must locate it with the Ultrasound, then cut its shadow to get it out of the organ. Once it's out, you should laser it 2-3 times, and that will defeat it. After doing this for all the small Kyriaki that appear, suture every wound(You need to use the Antibiotic Gel for the small cuts made by cutting the Kyriaki Out.) After every wound has been taken care of, 3 large wounds, 2 diagonal and one straight up and down. These were caused by the boss Kyriaki, whose occasionally accompanied by another small one. If it is with a small one, defeat that first just like you did the other small ones. When you're ready to defeat the large one, do a search for it, cut it out, and laser it just like you normally would. However, after you do that, it goes back into hiding. You'll have to cut it out again, laser it again, then repeat the process. It usually take 3-4 hits to kill a boss. After you defeat the boss Kyriaki, simply suture what wounds are left over and Kyriaki is defeated.

This GUILT is found in Missions 2-9,3-2,5-2,6-4,6-7,Z-5,and X-1.

This is probably the worst GUILT in the game, because every operation with it involves alot of luck. Before the Deftera come, you must laser away any tumors in the Organ(The Big Tumors can spawn many tinier tumors.) After getting rid of the tumors, a Red and Blue Worm will spawn -- The Deftera. The Deftera will move around, and occasionally spawn tumors you must laser. This is where the luck comes in; You must wait for the worms to get close and combine. Once they combine, they'll form a sort of circle that you must drain. After doing that, the Deftera will sort of lose color. Repeat this process 2 more times, and the 3rd time, the Circle will start rapidly spinning, generating tumors, and causing fairly rapid vital loss. You should see yellow dots that you can cut. Cut all the yellow dots, and extract the the tumor- like substance it leaves. Then place the membrane on the hole left and gel it. Laser off any tumors, any close the patient up. Deftera ain't so bad, huh? Well, it can get worse. In every mission with a Deftera, theres one part where you must deal with 2 pairs of worms at once. The number one difference between these is that if you're draining a combined pair, and a lone Deftera worm bumps into that pair, the drain sequence will be interrupted, forcing you to try again. The easiest way to get around this is to wait until both pairs happen to combine(Which does happen often.) After they do, drain them both. Just be careful, as you must only drain one the third time they combine, or else the vital cause by the rapid spinning and tumor generating will be too much on the patient. Just be careful, and Deftera will be simple.

This GUILT is found in Missions 3-4,6-7, and X-2.

This is the GUILT that most people get confused about, but once you get down to it, it's really quite simple. You see, the way Triti works is that it's basic structure is a Triangle with a thorn on each tip. To defeat it, you must extract all 3 of the thorns and then the triangle using the forceps. However, every Triti Operation usually has 8-15ish Triangles, and when you extract one, if certain conditions are met, more Triti will grow. Obviously, this isn't good. but just what are these conditions that cause the Triti to grow? Well, for one, if a Triangle is extracted, and another triangle has 2 thorns on the same side, a new Triangle will grow. However, the exception to this rule is if there isn't space for another triangle, then removing the triangle has no effect. You need to be hasty when extracting the Triti for this reason: If you remove all the right thorns so that no new Triti can grow, and grab a Triti while a thorn is regrowing itself, then more Triti will appear because you weren't fast Enough. Obviously, this can be very difficult, which is why I advise that you go slow and only try to remove 2-3 Triti Triangles at a time. There is one more Rule of Triti regrow which can sometimes make or break a mission: If there is an isolated triangle, and it has 1 or more thorns in it, it will grow new triangles on all sides. So when you're getting ready to remove the last Triti, leave 2 connected Triangles, wait for every thorn to regrow, then extract every thorn and get both Triangles so there is never an Isolated one. If you just follow these simple rules, you'll do well in extracting the Triti.

This GUILT is found in Missions 3-10,5-3,6-7, and X-3.

The Tetarti is a pain in the ass to pull off an S or XS on. This is mostly because you can't make a mistake, which these damn things tend to cause alot. Okay, now that I'm done venting off some steam, lets start destroying the Tetarti. First, usually when these missions begin, there will be some strange Tumor like substances to destroy before they will appear. There will be three, one purple, one green, one yellow. They keep growing, so you'll have to move fast, because if these things grow too big, they'll will rupture a bit, damaging the patient. To destroy these things, Get out the syringe and inject each tumor with the same color liquid. When you do, you'll see yellow dotted lines you can cut. Cut them, then excise the tumor. Place the membrane over the hole, and gel it up. Do the same for all 3 tumors, then the Tetarti appear. There are 3, one purple,one green, and one yellow. Just like with the tumors, you'll want to inject them all with the same color. Heres where most people mess up: The Tetarti keep moving, so injecting them with the proper colors is fairly difficult. They turn rather suddenly, so I usually wait until they get to the end of the organ and turn before injecting them. To damage them, you must inject all 3 with the liquids before they disappear. You must usually do this 5-6 times, and if you accidently inject the incorrect color into the Tetarti, several new tumors will appear that you must excise. Be very careful, stay calm, and focus, and the Tetarti will be easy.

This GUILT is found in Missions 4-2,4-4,5-4,6-3, and X-4.

Pempti is very simple to deal with. When it starts, you will see a large amount of mist on the organ, and a circle can appear and disappear in it. You must take out the Syringe with the orange vial (Only available with the Pempti Missions.) Inject the vial straight into the circle to destroy a bit of the Mist. Do this again, a little more of the Mist will be destroyed, and the Pempti Core will reveal itself. You must use the laser to destroy it. After doing that, it will disappear into the Organ and send out many smaller cores. There are three of cores in can send out: The Pink Cores, which will pop from the main core, wait for a second, then make a quick cut on the organ, the Blue Cores, which appear 5 at a time, will wait for a few seconds, then quickly cause several tumors to appear, which you must laser off then gel up the holes they leave, and finally, there is the Spinning Cores, Which appear quickly and cause much damage until destroyed. The pink cores are easy to kill. Simply laser them after they appear, and you'll destroy them all before they cause any damage. The blue cores are the trickiest. Destroy 2-3 of them before they cause any tumors. Now, since they are virtually invicible while making tumors, use that time to laser away any tumors they caused and gel up the holes. Once they make it back down, laser the remaining ones. The best advice that I can give for the spinning cores is to watch the main core, and when he sends them out, focus the laser right on him. That way you can destroy most of the spinning cores before they even get out. Now, in order to actually damage the Pempti,you must wait for the Core to reappear outside the organ, then laser it. After 5-8 hits of this, the Core finally goes down. Before I close out here, there is a few more notes for you:Because you must use the laser so much in the Pempti missions, you have an unlimited laser. Also, the order the Pempti sends out the different types of Cores is random, however, it can only so out one type of core a maximum of 2 times in a row. Just be careful in how you laser things, don't let the cores get the upper hand, and you'll find that Pempti is really easy to destroy.

This GUILT is found in Missions 4-6,4-8,4-10,6-6, and X-5.

Paraskevi is a fairly straightforward GUILT. When you start these Missions, theres always some open lacerations. Suture them up, and the Paraskevi appears. To defeat the paraskevi, you must laser the tail, then use the scapel across its body. This will cause 2 more cuts to appear, and will split it's body into 2 parts. You must repeat this process, Lasering the tail of the new worms and cutting it into 2, and keep repeating this a total of 4 times to bring the Paraskevi to it's smallest point so you can laser it's tail and extract it, then keep this up by doing the same to every other made, cutting everything to its smallest point, where you can easily extract it. There should be a total of 16 Tiny Worms you extract to fully defeat the Paraskevi. That's basically it, although there is one more key factor in these missions: If the Paraskevi burrows into the heart, the patient dies. You usually start several organs away, so you wanna stop the Paraskevi before it burrows deeper, for if the Paraskevi burrows through the Organs and you chase it all the way to the heart, it can easily turn the tides of the operation. So be careful.

This GUILT is found in Missions 5-6,6-4,6-7, and X-6.

The Savato is about as close to the final boss as you're gonna get in this game. When you see it, it will be surrounded by a Web. Before you can damage the Savato, you must destroy the web. To destroy the web, use the scapel on it. This will cause the scapel to melt, forcing you to wait before you can use another one. This process is slow, but you'll have to keep it up to destroy the web. Occasionally, the Savato will create another part of the web and also spawn some Baby Savatos. Just cut that part like normal, and use the laser to destroy the Baby Savatos before they can combine to form a Blue Savato, which can really damage the patient. Once you destroy the web, the Savato will run to another part of the heart to form another web. Destroy this web like the first one, and It'll create another one. after destroying the third web, It's time to damage the Savato. The Savato has 2 attacks during this part: He can create 3 small wounds on the Heart, and he can also create a large wound that Baby Savatos come out of. Destroy them fast. To damage the Savato, use the laser on him multiple times. The fire behind him will die down a little bit each time. Once the fire is completely dead, use the scapel on him. After that, he will run. Once he does, you'll have to repeat the process of lasering him. After you laser and scapel him, you must do it one more time. But that time, after you use the scapel on him, you must inject him with a black liquid. After that, he will begin to go crazy, running around the heart making so tons of wounds. After a second or two of this, Derek will use a story Healing Touch. However, you still have your normal one. So quickly use your Healing Touch, and then the two combined will cause time to stop. That's right, actually stop. Quickly inject the Savato with the black liquid again, and it will die. Every wound in the heart will magically heal itself, so Savato will be complete after that.

This GUILT is found in Missions 5-9,6-8, and X-7.

  • Time: 5:00
  • Vitals:
    • Start:80
    • Max:80?
  • Special Bonuses:
    • Vitals Stayed Above 60/70/75
    • No Mistakes
    • Completed with 240/270/275 Left
    • 3/4/6 Cool's Earned
  • Rank Scoring:
    • S Rank: 5200 Points
    • XS Rank: 5400 Points

This is the First Operation, and as such,this is pretty simple. When you start, the nurse is going to ask you to suture the 2 wounds that don't have glass in them. For Suturing, make small zig zag marks on a scar, that don't spread too far apart. For more help, refer to the Using the Tools Section.

Now take the forceps and carefully pull the glass out. You don't have to be lightning quick to score an XS on this mission, just make sure you don't make a mistake. To pull out the glass, hold A+B on the glass, and, without letting go, pull it out of the wound in the opposite direction it's lodge in there, then once you receive an "OK" message, you can put it on the tray. For putting it on the tray, try to make sure that the glass is right in the center of the tray before you let go to earn cools.

After removing both shards of glass, Spray the Antibiotic Gel(Spray it fast over the cuts), then spray the gel over the cutting line. For cutting, just keep it slow, and go in a straight line. The Biggest mistake I made when I was first playing the game is screwing up the cutting.

Once you've finished the cut, Pull the glass out the same way you did before(These are easier as they are a bit smaller.)

After that, Spray the gel over the cuts, like you did before.

Finally, Suture the wound, as you did before, only instead of just small zig zags, I like to just have my suturing touch the tip with the big cuts. Spray the sutured cut to disinfect it, and finally, all thats left to do is place the bandage.

For the bandage, click the icon, then start from a little lower than the very bottom of the cut, about right in the middle, and press and hold A while you lift it to a little higher than the middle of the top. After that, you're done.

  • Time: 5:00
  • Vitals:
    • Start:99
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 210/240/260 Left
    • 1/2/3 Cool's Earned
  • Rank Scoring:
    • S Rank: 4600 Points
    • XS Rank: 4700 Points

Start By Spraying the Gel and Cutting him open. This is a little harder than last time, as last time was straight up and down while this one is curved. Don't panic, though, you can do it as long as you take it slow.

After Opening him up, Mary will ask you to restore the patients vitals. This can be done by taking the Needle, Filling it up with the Vital Restoring Juice(The Green vial that appears when you switch to the needle)by pressing A, then going to a spot and giving that spot the juice. I usually like to inject the juice into the reddish area in the middle of the organ, but I don't think it really matters.

After that, Mary will ask that you locate the tumor. Switch to the ultrasound, then push A to located the tumor. You should see a shadow after you find the tumor. Then Tumor is a little south of the red mark in the middle of the organ that I pointed out before. Once you see the shadow, you should notice the yellow mark going up and down it. Simply cut that with the scapel(It's not really possible to make a mistake like when you perform the initial cut.)

After that, switch to the drain, push A to suck the juice outta the tumor, then cut the yellow marks that appear(Like before, it's almost impossible to make a mistake), Then take the tumor out, similiar to how you removed the glass in the last mission, except that you don't have to pull it out any special way, just grab it and put it on the tray.

After that, using the forceps again, grab a special membrane designed for curing holes like that, place it in the middle of the hole, then simply spray it with the gel.

Close him up, use the spray, and bandage him just like last time, and it's operation complete.

  • Time: 5:00
  • Vitals:
    • Start:99
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 200/220/240 Left
    • 1/2/3 Cool's Earned
  • Rank Scoring:
    • S Rank: 5300 Points
    • XS Rank: 5400 Points

This is alot like your last mission. Spray the gel and cut him open(Be Careful!), as you should be used to by now, then you should see two small inflamed sores. Be careful, and take out the needle. Use the Blue Vial this time, and inject it only into the 2 sores(Injecting it anywhere else will be considered a miss.) Be careful, as the needle with the blue vial is a bit touchy.

After taking care of the sores, find the tumors. Theres one in the top left and right corners of the organ, plus one in the middle of the bottom. Extract them all like you did in the last mission(Locate The Tumor, Cut It Out,Drain The Juice, Cut It to Detach It, Extract It, Place the Membrane over the Hole,Gel the Membrane In.)

After taking care of the tumors, you can close the patient up. Operation Complete.

  • Time: 5:00
  • Vitals:
    • Start:99
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 150/180/210 Left
    • 1/2/3 Cool's Earned
    • Fewer than 15/12/6 Blood Pools
  • Rank Scoring:
    • S Rank: 5100 Points
    • XS Rank: 5200 Points

This Mission may seem difficult at first,but if you try it a couple times, it will be real easy. Make sure to use the vital restoring Juice that you used in [Episode 1-2]Learning the Ropes if you run into trouble(Although I suggest you use it if vitals go down to 35 and below.)

First, Cut him open like you have in the past(Slow and Steady.) For this operation, instead of the Ultrasound, you have the Magnification. To use the magnification, simply push A on an area to zoom in.

Now, you'll notice the polyps(The Little Bumps) at the top. Zoom in a little higher then where the actual polyps are, as the magnification is kinda screwy at the top and bottom of the screen. Use the laser to burn the polyps, drain and blood that occurs, then spray gel over the holes.

More Polyp groups will appear, so you'll have to do this several more times.

To focus the magnification on a different area, use the magnification on any spot when zoomed in, then again zoom in on the area you wanna look at(Remember the rule for when you wanna look at the top or the bottom of the screen)The first one is at the top, then the bottom, then the top again, then the bottom again, then the top rightish.

After destroying all 5 groups of Polyps that appear, close him up like you have before, and your done.

  • Time: 5:00
  • Vitals:
    • Start:70
    • Max:80
  • Special Bonuses:
    • No Mistakes
    • Completed With 120/180/210 Left
    • 2/2/3 Cool's Earned
    • Vitals Stayed Above 15/20/25
  • Rank Scoring:
    • S Rank: 6100 Points
    • XS Rank: 6200 Points

This can be a tough mission for new players, so just stay calm. Do the opening cut as you've done many times by now. Grab the Needle, and use the blue vial. Special Injections are, unfortunately, VERY touchy, so be very careful and watch your aim. You want to use the injection on the many inflamed sores you see. Each Injection should be able to cure 4 small sores, 2 large sores, or 1 Large Sore and 2 Small Sores.

After you take care of all the small sores(Making a mistake your first time is not the end of the world. The first time I did this I made a mistake every other shot.)It's time to remove those tumors.

Remove them the same way you have in the past:Locate, Cut, Drain, Cut, Excise, Membrane, Gel. The Four Are Rather Close To Each Other, so don't go looking in some random area.

After removing all 4, Simply Close Him Up as you've done so many times before, and your done.

  • Time: 5:00
  • Vitals:
    • Start:10
    • Max:30
  • Special Bonuses:
    • No Mistakes
    • Completed With 200/225/240 Left
    • 5/8/10 Cool's Earned
  • Rank Scoring:
    • S Rank: 5800 Points
    • XS Rank: 6000 Points

Don't Let the Low Vitals Frighten You, This is a fairly easy operation. A Quick Note Before You Begin: If Vitals Fall Below 15, Raise them up using the needle and the vital juice. You don't wanna risk it. Now then, on to the actual surgery.

When you start, you'll need to use the defibrillator. Push the Wiimote and Nunchuck towards the screen, Then when you see the bar, push Z+B right when it lands in the green area. Screwing up will cause a small drop in the vitals and you'll have to retry.

After that, Suture the small wounds you see, Then make a cut after that to get to the heart. Remember when you pulled out the glass in mission 1-1? Time to do that again. Theres 6 pieces here, and you'll have to pull them out just like the first time, then use the gel to cure the small wounds.

After that, a Giant piece will lodge itself from inside the heart. Pull it out very carefully, and then place it in the tray. Suture the wound, and it will then remake itself. You'll see Derek really focus and a Star will appear. Thats called the Healing Touch, but I'll explain that more later.

Suture the wound again, Then Suture the initial cut, and then you've finished the operation, as well as Chapter 1.

  • Time: 5:00
  • Vitals:
    • Start:99
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed with 180/220/240 Left
    • 2/3/3 Cool's Earned
    • Less than 6/3/2 Thrombi Pass Through
  • Rank Scoring:
    • S Rank: 6900 Points
    • XS Rank: 7000 Points

Alright, begin this like you would any operation, cut him open. You'll be asked to use the magnification inside, but it this time the Magnification almost always takes you to the same place.

Use the ultrasound and you'll notice the blue dots. Clip them with the forceps, cut them open, then drain them, then use the gel. If one makes it to the end, Vitals will drop a bit. Remember to raise them up.

After you take care of around 5-10 Thrombi(the blue dots), they'll start going real fast. Use the ultrasound and clip as many as you can (One or Two may make it to the end), but don't cut them. Eventually, you'll see the star pattern like you saw in the last mission. The Thrombi will begin to move very slowly. Cut and Drain the ones that you've already clipped, then cut and drain a few more before Angie gives you the OK.

Close him up, just like you have before, and then it's operation complete.

  • Special Bonuses:
    • Healing Touch Activated
    • 2/3/4 Skilled Healing Touches
    • 3/2/1 Passable Healing Touches
  • Rank Scoring:
    • S Rank: 2000 Points
    • XS Rank: 2000 Points

Alright, We will now learn how to use the Healing Touch. The Healing Touch is an Innate Ability that Derek has which slows down time so Derek may do things faster. Obviously, this is a very useful skill, and some operations even require that you use it.

To Use it, Press and Hold Z and B and draw a star pattern on the screen. You'll know it works when you hear a noise. This operation has no time limit, and you can make as many mistakes as you want. Just draw 5 stars To win(I suggest you follow the guideline on the screen.)

As for the special bonus, make sure you get both the skilled and passable star bonuses for the best rank. Unfortunately, I am not sure as to what this game considers passable or skilled, but If you keep trying, you'll eventually get it. Also, if your going for the special bonus, make sure you don't mess any up. If you do, thats okay, but you won't recieve the first special bonus, which is necessary for that S/XS.

After this operation, you may use your new Healing Touch at any time in the game using the same method.

  • Time: 5:00
  • Vitals:
    • Start:70
    • Max:80
  • Special Bonuses:
    • No Mistakes
    • Completed with 60/90/150 Left
    • 4/6/7 Cool's Earned
    • Max Chain Over 30/40/50
  • Rank Scoring:
    • S Rank: 7200 Points
    • XS Rank: 7300 Points

This one isn't so bad if you know what you're doing. Begin by making the opening cut. Once in there, you should see the Aneurysm(The Reddish thing with Vein Lines.) The Aneurysm will keep getting bigger, and if it gets to big, it will rupture, causing large amounts of damage. Therefore, you should hurry.

Use the Magnification to zoom in there, and Switch to the needle to inject the orangish liquid into it. After that, You're going to want to cut the yellow lines, like you did when you were cutting open the tumor, and extract it just like you would extract a Tumor. Then Drain the Blood that Appears, grab one Vein Line with the forceps, and pull it towards the other to connect them. Then Suture it like a wound.

After that, Unzoom, and wait. Soon, you should see another one grow. Do the same method as the first one(Don't let it get too big!) and then unzoom and wait again. This time, there are 2 that appear. My advice would be to do each step to both of them at the same time(Inject them both with the Orange Liquid, then Cut them both out, then extract them both, then drain both veins, then clip both veins, then suture them.) You wanna do them both at the same time so niether one ruptures.

After that, heal up the vitals a little if you need too, then unzoom to greet the next pair of Aneurysms. Get rid of this pair the way you got rid of the last pair.

After that, Unzoom, and Use the Healing Touch(Just like in the last mission.) Four Aneurysms Will Appear this time, but with the Healing Touch activated, you can handle it. Even with the Healing Touch, I still suggest you use the same method as you did when the pairs appeared, and just do one step with all of them before moving on to the next step.

After you handle these four, close the patient up, and you're done.

  • Time: 3:00
  • Vitals:
    • Start:40
    • Max:65
  • Special Bonuses:
    • Less than 3/2/1 Hemorrages
    • Wound did not Reopen
    • 4/6/8 Cool's Earned
    • Max Chain Over 8/10/20
  • Rank Scoring:
    • S Rank: 4500 Points
    • XS Rank: 4700 Points

Ah, and easy one. Cut her open, like you normally would, and inside you'll see 2 large wounds and 4 small wounds.

Begin by suturing up the small wounds, as you know how to do.

Once you've taken care of those, Lets move on to the larger wounds. The first thing you wanna do is drain the blood. Then, because the wound is too large to suture, you'll wanna clip the sides together. To do this, grab the forceps,then grab one side of the wound and pull it towards the other. After that, you can suture it like it's any other wound. You're going to want to go fast whenever you deal with these big wounds, though, because the wounds could reopen or the blood could regather.

After finishing that wound up, do the same for the other wound, then close her up. Good Work, Doctor.

  • Time: 5:00
  • Vitals:
    • Start:45
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Wound did not Reopen
    • Completed with 120/150/180 Left
    • Max Chain Over 30/40/50
  • Rank Scoring:
    • S Rank: 8500 Points
    • XS Rank: 9000 Points
  • GUILT:

This will be your first encounter with the GUILT. Cut her open like last time, and you'll see the wounds have reappeared, but this time there are 3 small wounds and 3 large wounds. Suture the wounds up like you should know how, and then another wound will somehow appear.

Using the ultrasound, you can find a mysterious blue creature inside the organ. Grab a scapel to cut it out, then once it appears use the laser to hurt it. It only takes to hits with the laser to defeat it, but then 2 more appear in the organ.

Repeat the process(Don't worry about the Wounds for Now.) and defeat both of the blue creatures. After that, suture the wounds(You can use the antibiotic gel on the small wounds made from cutting the creature out.)

Once everything has been sutured, 3 large wounds will appear in the middle of the organ. Don't worry about the wounds for now, just use the ultrasound. You should find a larger blue creature. Cut it out and attack it with the laser, and it goes back into hiding. Keep repeating the process of locating it, cutting it out, then lasering it. After 3 hits, it's down.

Suture the wounds, and remember to use the gel on the really small ones. After that, close the patient up, and you've successfully defeated the Kyriaki Strain of GUILT.

  • Time: 5:00
  • Vitals:
    • Start:99
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed with 200/220/240 Left
    • Fibrillated Less than 6/4/3 Times
    • Max Chain Over 8/14/16
  • Rank Scoring:
    • S Rank: 4700 Points
    • XS Rank: 5000 Points

Okay, before we begin, you have to know that you're operating on a little girls heart(No Pressure...). Occasionally, her Heart will flatline and you'll have to use the defibrillator. If you move fast enough, That could only happen once. The slower you go, though, the more it'll happen. You should remember how to use the Defibrillator from The last operation in Chapter 1, [Episode 1-8]Life or Death

Now then, begin by cutting her open. Spray the gel on the heart and switch to the scapel, and she will begin to flatline(Don't Worry, this cannot be avoided.) Use the defibrillator, then cut the heart open. It's time to work quick, as periodically through the next part, her heart may begin to flatline again, forcing you to use the defibrillator again.

First, Drain the blood. Then, cut the yellow lines on the valve. More Yellow lines will appear, cut them, then even more yellow lines will appear, so cut them too. After that, remove the valve, grab the replacement valve, and place it where the first valve was(This can sometimes be a bit touchy, so be careful.) suture it in almost like a wound(I go from Right to Left, though I think you can do it from Up to Down.) Quick fast strokes are all it takes.

After that, suture the heart wound(This doesn't require a bandage.) And suture the first wound. You just finished Chapter 2.

  • Time: 5:00
  • Vitals:
    • Start:75
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 120/150/180 Left
    • Max Chain Over 30/40/50
  • Rank Scoring:
    • S Rank: 8300 Points
    • XS Rank: 9000 Points
  • GUILT:

This Mission is actually very similiar to [Episode 2-9]Please Let Me Live. In this mission, you must once again defeat the Kyriaki creatures.

To start, open the patient up, and suture the wounds like normal. There are 5 small ones and 2 large ones, both of which you should be used to. After that, the first Kyriaki shows up. Don't worry about the wounds yet, just focus on defeating him. Just like before, use the ultrasound to find him, the scapel to cut him out, the laser to kill him(2 hits) and then suture the wounds he made(Remember to use antibiotic gel on the small one!)

After that, two more appear. Use the same method, and don't worry about the wounds till the very end. After defeating these two, suture any wounds they left, then take some time to raise the patients vitals.

After that, the big guy appears. Locate him, cut him out, laser him, and he goes back into hiding. Repeat this process 2 more times to defeat him, then suture and gel any wounds left over.

After that, close the patient up, and your done.

  • Time: 5:00
  • Vitals:
    • Start:75
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 80/120/150 Left
    • Max Chain Over 30/40/60
  • Rank Scoring:
    • S Rank: 7700 Points
    • XS Rank: 7800 Points
  • GUILT:

In this Mission you'll deal with a new GUILT, the Deftera. First, like all operations, cut the patient open.

When you get in there, you'll see some tumors. Simply laser them to get rid of them. Be careful, though. The Big Tumors can generate smaller tumors.

After you destroy the initial tumors, a red worm and a blue worm will appear. These are the Deftera. They'll move around the organ, and occasionally spawn more tumors. Destroy the new tumors they spawn in the same way.

To Defeat these creatures, you must wait it out until the red and blue worms meet. Once they do, they'll create a sort of circle. Use the drain right in the middle of this circle to damage them. When they come out of the circle, you'll notice they've suffered some color loss. Thats good. Repeat the process of waiting them out, lasering what tumors they drop, then draining once they combine.

After the third time you do this, The circle will start moving rapidly. Eventually, you'll see yellow dots that you can cut out.(Similiar to a Tumor.) Cut them quickly, as while the dots are there, tumors are generated rapidly and vitals shoot down. After cutting out the Deftera, you can use the forceps to excise it, then grab a Synthetic Membrane, place it on the hole, and use the antibiotic gel to meld the membrane in.

After that, laser any tumors that are still there. Close up the initial wound, and it's time to move to the next area.

Just like usual, spray the gel, make the cut, enter the body. There's no initial tumors to laser this time, the Deftera just appears. This time, there are 2 red worms and 2 blue worms. If one worm mizes with a worm of the same color, they drop the vitals a bit and leave a tumor. Unfortunately, there is no real way to guard against that, making this part very difficult. Also, if a lone worm comes into contact with two combined worms you're draining, it'll screw up the process, causing the worms to break apart and forcing you to try again. My best advice is to not even try to drain anything unless both pairs are combined(Which actually does happen a lot.) Then drain both of them.

You want to be careful with this method, though. If you drain them both, and it's the last needed drain for both of them (Causing both combinations to rapidly spin.) There may be too much drop in the vitals (It's happened to me before.) So Drain both combinations the first 2 rounds, then the third round, wait for them both to combine, but only deal with one. Extract the Deftera, place the membrane, gel it in. Then drain and defeat the other Deftera, Seal the hole like you normally would, laser any tumors, raise the vitals, seal her up.

  • Time: 5:00
  • Special Bonuses:
    • Did Not Approach Miss Limit
    • Completed With 180/210/220 Left
    • No Healing Touch
  • Rank Scoring:
    • S Rank: 6000 Points
    • XS Rank: 6000 Points

Ugh, this is a tough mission, and the time bonus is brutal. But hey, lets start.

When you begin, you'll see 4 screws you must twist off. Stick the scapel in the middle, then twist your hand one way or another to unscrew it. For the Bottom-Left Screw, Twist your hand left. For the Bottom-Right Screw, Twist your hand right. For the Top-Right Screw, Twist your hand left, and for the Top-Left Screw, Twist your hand right.

After getting that done, it's time to switch the voltage. Using the forceps, grab one of the pegs, pull it towards yourself(Literally) then push it into another hole. The pegs need to be in the top hole on the left side and the 3rd from the top hole on the Right side.

After that comes the hard part: lasering the panels. You'll see a bunch of hexagonal panels floating in front of a red core. What you need to do is laser off every panel to get to the core. Easier said then done, trust me. You get one free miss, but two and you're dead. There are two ways too miss: Laser the Red Panels, or lasering something that isn't a panel. The Flashing Red Panels move after time, so be careful if you try to laser a panel near it, as sometimes it can move to the one you're lasering, resulting in a miss. After a while, the flashing red panels seem to disappear. They reappear eventually, but don't move, and disappear again over time. They keep this pattern up for the rest of the "Operation", so you can easily laser any panels near them without fear.

After destroying all panels, you must destroy the core. You only have 30 seconds to do this, so HURRY. If you're not going for a perfect rank, I suggest you use the Healing Touch now. Several rows of flashing, rapidly moving panels will protect the core. If you hit one of those, you lose. So just take it slow, and focus on lasering the core. If a Row starts heading towards you, stop for a second, let it pass, then continue.

After destroying the core, it's Mission Complete. Good Job!

  • Time: 5:00
  • Vitals:
    • Start:99
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 120/180/210 Left
    • Inflamation Remained Below 10/6/3
    • Completed Before 7/5/5 Jolts
  • Rank Scoring:
    • S Rank: 6800 Points
    • XS Rank: 6900 Points

Before you start this mission, note this:Periodically, you'll feel a slight shaking of the plane. This is okay, but once it starts shaking it'll soon lead to a giant rumbling, during which any tool(Even the Antibiotic Gel!) will leave a cut on the organ. So once it starts shaking, do only 1 or 2 more things before the rumbling occurs. If you do that, you'll be fine.

Now then, on to the actual mission. Cut him open, then use the ultrasound to locate a hole. Using the scapel, cut the hole out, drain it, then use the gel to fix it. The holes spawn in random places, so there is, unfortunetly, no real way of telling where they're gonna appear next. Keep repeating the process of Finding a Hole, Cutting it Out, Draining it, Using the Gel. You're going to have to do this a total of approx. 12 times before he's saved.

After you're done cutting and draining, simply close him up and it's operation complete.

  • Time: 5:00
  • Vitals:
    • Start:85
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 120/180/210 Left
    • No Healing Touch
    • Less than 13/8/2 Membranes Multiplied
  • Rank Scoring:
    • S Rank: 6100 Points
    • XS Rank: 6200 Points
  • GUILT:

Alright, In this Mission we will deal with the third and most annoying GUILT:Triti. Before we begin this mission, You should probably read through the Triti part of the "Dealing With GUILT" Section. I'll give a quick rundown here:Triti is a triangle, with 3 thorns in it. To defeat it, you must remove all 3 thorns from it and then the triangle, using the forceps. However, doing so causes more Triti to grow in other areas. That's explained in full detail in the "Dealing With GUILT" Section, but for now, simply follow my directions.

First, just like any operation, cut Reuben Open. Once inside, you should see the Triti. You have to act fast after starting every step, or else the Thorns will regrow(Which usually results in more Triti growing, which isn't good.)

Alright, I've made an ASCII diagram for you. Simply follow the directions, and extract what you need to in the proper steps(Make sure you use the Forceps!)Some last Notes before you start: If any thorn breaks into a mist, you should drain the Mist before continuing, as that Mist can grow new thorns. Also, if a thorn regrows before you've finished removing the Thorns/Triangles in a Step, Wait for ALL the thorns to regrow then retry the step. You have plenty of time to do this mission, but you don't wanna fail because you made a stupid mistake.

STEP ONE:

   *-----*
  / \   /
 /   \ /
*-----6-----*     3
 \   / \   / \   / \
  \ /   \ /   \ / 7 \
   *     *-----2-----5
              / \ 8 /
             / 9 \ /
            1-----4

Alright, After Completing Step One(If any new Triangles grow then restart unless you have a very good understanding of Triti) You're gonna wanna wait for the thorns to regrow(You should Restore the Vitals while you wait.) After every thorn regrows,you need to move on to Step Two.

STEP TWO:

   4-----3
  / \ 9 /
 / 8 \ /
5-----2-----*
 \ 7 / \   / \
  \ /   \ /   \
   6     *-----1

After that step, you need to let the thorns regrow again(Raise the Vitals Some More!) After all the thorns regrow, it's time to finish off the Triti.

STEP THREE:

      4-----3
       \ 5 / \
        \ / 6 \
         2-----1

Once you've finished Step Three, just suture Reuben up, and you've beaten Chapter 3.

  • Time: 5:00
  • Vitals:
    • Start:90
    • Max:99
  • Special Bonuses:
    • No Mistakes
    • Completed With 60/120/180 Left
    • Max Chain Over 5/10/12
    • Toxins formed less than 10/5/3 times
  • Rank Scoring:
    • S Rank: 4400 Points
    • XS Rank: 4500 Points
  • GUILT:

Alright, This missions is a little odd. You'll have to perform several operations in this mission(You choose what operations you want to do.) You'll have to do about 3, but each one is basically the same. To begin, like always, cut the patient open.

Inside, you'll see a new GUILT:Tetarti. First, take the syringe and inject the Red Serum into him. He'll burrow into the organ similiar to the Kyriaki. Use the Ultrasound to find him, then cut him out with the scapel. Inject him with the Serum again, and he'll hide again. Repeat the process. After you inject him the third time, he'll stop moving. Use the forceps to extract him, then when he is on the tray use the scapel to cut him open. Drain the fluid that comes out, then stitch your patient up.

Repeat this process for 2 more operations and it's mission complete.

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