Blaster Master: Overdrive is an action-adventure game that takes place on an Earth infected by an aggressive, polymorphic virus. Poor, defenseless animals worldwide have been turned into flesh-eating, hemoglobin-swilling terrors. Fortunately, the world has Alex, who happens to be one of the world's foremost biologists and specializes in viral mutation profiles and genetic manipulation. Every studious biologist facing imminent global annihilation needs a sweet ride, and Alex is no exception. He has S.O.P.H.I.A., a shape-shifting, gas-guzzling, projectile-spewing paean to destruction on four wheels. Things look grim, but with Alex and S.O.P.H.I.A. on the case, the world just might have a chance.