They've been messing around with it, but as of yet, we don't know.

Bloodmoon was based in a part of north-skyrim, so im hopeing yes.

Based off of oblvion there might be a diesea which you contract and if not treated you will be come a werewolf. You have to remeber that this is skyrim the land of bitter cold and power also dragons so with all these challenges where would Bethesda put in a powerful werewolf. This is a great idea but i highly doubt that werewolf diesea will come into play in Skyrim :)

Well if horkers are making a return (FROM BLOODMOON), werewolves are probably coming back to.
Even if you don't necessarily turn into one.

It certainly possible and it would fit in well with the environment but nothing has been confirmed. And to Wymerm1. 1). Diesea isn't a word (I assume you mean disease) 2). How does Skyrim being cold and having dragons seem to make you think that werewolfs wont be part of it? You think that the only enemies in the game are dragons and avoiding hypothermia?

Hopefully you can. What about Vampires?