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This topic inspired by somebody (cant recall the name) who referred to using modded saves as "cheating."
In fact, he said something along the lines of "I despise cheating."
Well, lets take a look at the definition of cheating, shall we?
from http://www.merriam-webster.com/dictionary/cheat Intransitive verb, 1a: To practice fraud or trickery; 1b: to violate rules dishonestly
Hm. Well, look what we have here. 1a doesn't necessarily apply. 1b would be the definition that fits, IF Skyrim had "rules" per se. Unfortunately for you, Skyrim is singleplayer. There are no people to get an advantage over; there are no rules to violate dishonestly; there is no "cheating" being done.
Granted, using Modio or like programs to modify saves falls into a morally grey area, and is technically illicit. But such rules are/were in place to stop people from gaining advantages in multiplayer games, which, need I remind you again, Skyrim is not.
Modifying Skyrim saves allow for you to play the game "as it should" be played. Little to no essentials, cut items/shouts/spells made available, enhanced magic, etc. Where is the shame in this?