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Honestly, all this complexity on this and sniping is making my brain melt. And I got a 4.0 GPA in senior year of high school, while taking AP chem, calc AB, and environmental science.
Honestly, I'd say to hell with trying to influence the RNG that only keeps getting more and more difficult to crack and buy Datel Powersaves. I don't have one, though I will likely get one simply to avoid the charm BS. I would want to be able to get all good legit charms, and maybe 1-2 non-legit but for good reason ones. Namely, combo plus+10, (shot type) up +5, evade dist +10, and a couple others. I have nothing wrong with hacks if they don't actually break the game.
Thank god that Crapcom got the messages about everyone manipulating the RNG and they switched back to rotating tables that change on game load.
While math would help in general, none of the above courses you noted would help in understanding charm tables. A couple semesters coding in a lower-level language like C or assembler, plus some comp sci would likely make it dead easy to understand.
It's a simple concept in general, and if you want, I'd be happy to provide a description if the previous ones in this thread didn't help you.