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the main reason is because each patch better be applied to clean (unpatched) iso, to avoid any possible error in the game. secondly, most MHDOSAG+ quests have 3-4 monsters in a single quest. and to make it worse, those monsters love to hang around together.
so, keep your MHDOSA2+ for casual play, and make a separate disc of MHDOSAG+ to experience getting stomped by 3 los at once ;D
Damn.. i start to lose interest in Games I must've getting old