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I got the game today, runs slowly on my laptop with an 8400gt card, at least I can drive around but with some lag, hopefully R* release a patch that will make the game run just a bit faster, I don't care about awesome graphics as long as I can see and play without lag.
Anyway back to the topic, this error can be fixed by pausing your anti-virus, it worked for me both times I used the game, with having the anti-virus running it brought the error screen. Also if I turn Vista from 32 to 16 bit it runs and loads a little faster, hope this helps and I hope all problems can be fixed.