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Samurai Warriors: Chronicles Tales of the Abyss Kid Icarus: Uprising
I'd say those 3 games have more than 100 hours worth of content.
Mario Kart 7 can also give you 100+ hours if you enjoy it enough. As for Dragon Quest 9, you shouldn't have much trouble reaching 100+ hours. The game itself is about 30 hours, but the post-game stuff takes quite a while.
And I suppose there's also Pokemon Black & White (and the 2nd games of them). They can last 100+ hours easily too.
Read the mania: http://www.fanfiction.net/~nonexistinghero In SA2, it's Super Sonic and Hyper Shadow.